There is a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to decrease afferent suffering transmission and produce analgesia. As a result, medication like clonidine that focus on alpha-two receptors can impact the transmission of discomfort. Clonidine is dispersed https://aloisz692bwr1.ourabilitywiki.com/user