Substitution at R3 with a halogen or alkoxy group (74f–74i) resulted in a slight rise in cellular potency With all the halide analogs (74g–h) showing highest the potency while in the group. Even further optimization resulted in the invention of 74i–j, with 74k as quite possibly the most Energetic compound https://codyhbsix.blog2news.com/32035847/the-5-second-trick-for-indazole-n-oxide