At this time, there are two kinds of studies on itaconate: Irg1−/− macrophages as well as regulatory influence of itaconate derivatives. These two effects have been complementary and discovered that the regulatory mechanisms of itaconate included alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription component 3 (ATF3) https://ricardobtmew.verybigblog.com/29320780/5-easy-facts-about-e-daporinad-described