High glucose one-way links to dysfunctions of glucose uptake and catabolism and induces superior oxidative stress, dysfunction of endothelial cells. Large hypertension causes cardiac and vascular injuries. Central being overweight is related to maldistribution of totally free fatty acid, overproduction of inflammatory molecules, and leptin resistance [21]. Name your assortment: https://www.directivepublications.org/journal-of-cardiovascular-diseases/